Set Appliance State:

Isolate Mains Power to appliance as per TOPs P4
Set Multimeter to Resistance Set meter to measure resistance
Disconnect plug from the flue thermistor
(If the appliance is not twin flued access can be improved by removing the three screws holding the panel at the top of the boiler)
Disconnect connector X401 from the PCB

Measurement:

Check for continuity (zero resistance)
between each of the two wires to the flue thermistor
(Pins 9 and 10 on X401).
Also inspect the full length of harness and
the connectors for any signs of damage.